Choi YJ*, Moskowitz JM, Myung SK, Lee YR, Hong YC.
* Department of Family Medicine and Center for Cancer Prevention and Detection, Hospital, National
Cancer Center, Goyang 10408,
South Korea
Published in:
Int J Environ Res Public Health 2020; 17 (21): E8079
Published: 02.11.2020
on EMF:data since 14.02.2021
Further publications:
Keywords for this study:
Brain/CNS tumor

Cellular Phone Use and Risk of Tumors: Systematic Review and Meta-Analysis.

Original Abstract

We investigated whether cellular phone use was associated with increased risk of tumors using a meta-analysis of case-control studies. PubMed and EMBASE were searched from inception to July 2018. The primary outcome was the risk of tumors by cellular phone use, which was measured by pooling each odds ratio (OR) and its 95% confidence interval (CI). In a meta-analysis of 46 case-control studies, compared with never or rarely having used a cellular phone, regular use was not associated with tumor risk in the random-effects meta-analysis. However, in the subgroup meta-analysis by research group, there was a statistically significant positive association (harmful effect) in the Hardell et al. studies (OR, 1.15—95% CI, 1.00 to 1.33— n = 10), a statistically significant negative association (beneficial effect) in the INTERPHONE-related studies (case-control studies from 13 countries coordinated by the International Agency for Research on Cancer (IARC); (OR, 0.81—95% CI, 0.75 to 0.89—n = 9), and no statistically significant association in other research groups’ studies. Further, cellular phone use with cumulative call time more than 1000 h statistically significantly increased the risk of tumors. This comprehensive meta-analysis of case-control studies found evidence that linked cellular phone use to increased tumor risk.


cellular phone | electromagnetic field | tumor | case-control study | meta-analysis


Mobile (cellular) phones